Maternal breast milk is the recommended form of enteral nutrition for preterm or low birth weight (LBW) infants as it contains immunoglobulins and lactoferrin which promote intestinal maturation and protect against inflammation and infection. Very low birthweight (VLBW) infants require greater nutrients than full term infants to fuel growth and brain development. However, maternal breast milk alone may not meet the nutritional needs of VLBW infants, and either human donor milk (HDM) fortifiers or nutrient-rich preterm formulas are needed. This clinical evidence summary was developed to provide a synopsis of the current clinical literature and study data specific to products available in the United States for human donor milk. There are a number of suppliers with various features available on each product. HealthTrust members have exclusive access to a product features summary profiling these attributes. It can be found within the contract package on the Member Portal. If you do not have access to the Member Portal, contact your local supply chain administrator or HealthTrust Account Manager to request a copy of the matrix.